18th Annual · January 2020 · In person

2020

27 faculty
32 recordings
22 slide decks

Symposium

Application of NIA-AA Research Framework

Saturday, January 18, 2020 · 8:15 am - 5:25 pm

7:15 am - 8:15
Check-in and Continental Breakfast
8:00 - 8:15
The ATN Framework: Background and Importance
Ranjan Duara, MD, FAANMount Sinai Medical Center
Watch 8 min

8:15 - 11:25

Session 1

Application of NIA-AA Research Framework in the Real World

Chair: Reisa Sperling, MDHarvard Medical School

8:15 - 8:50
Keynote NIA-AA Framework for Alzheimer’s Disease Research: Implications for Mild Cognitive Impairment
Ronald Petersen, MD, PhDMayo Clinic
Watch 27 min Slides PDF
8:50 - 9:10
The ATN Framework: Prediction of Progression from MCI to AD Dementia
Leslie Shaw, PhDPerelman School of Medicine
Watch 20 min
9:10 - 9:30
The ATN Framework: Prediction of Progression from Normal Cognition to MCI
Reisa Sperling, MDHarvard Medical School
Watch 21 min Slides PDF
9:30 - 9:50
The ATN Framework: The Importance of Lifestyle Factors in Predicting Progression
Jennifer Rabin, PhDSunnybrook Research Institute
Watch 19 min Slides PDF
9:50 - 10:10
The ATN Framework: The Good, the Bad, and the Ugly
David Bennett, MDRush University
Watch 16 min Slides PDF
10:10 - 10:35
BREAK
10:35 - 10:55
Application of the ATN Framework in African Americans and Caucasians
Tammie Benzinger, MD, PhDWashington University
Watch 24 min Slides PDF
10:55 - 11:25
Panel Discussion/Q&A
Moderator: Julie Schneider, MD
Watch 33 min

11:25am - 2:30 pm

Session 2

Application of Technology for Early Diagnosis and Assessment of MCI

Chair: Demetrius Maraganore, MD, FAANUniversity of Florida

11:25 - 11:30
Technology for Early Diagnosis and Assessment of MCI: Background, Importance and Trends
11:30 - 12:05
Keynote Assessment of the Aging Brain Using Computing Technology
Jeffrey Kaye, MDOregon Health & Science University
Watch 38 min Slides PDF
12:05 - 1:00
LUNCH
1:00 - 1:20
Biomedical Informatics and eHealth Core (BMI-EH), 1FLORIDA ADRC
Demetrius Maraganore, MD, FAANUniversity of Florida
Watch 29 min Slides PDF
1:20 - 1:40
A Novel Method for Assessing and Training Everyday Functional Skills
Sara Czaja, PhDWeill Cornell Medicine
Watch 16 min Slides PDF
1:40 - 2:00
The Brain Health Registry: Use of Web-based Technology for Detecting and Monitoring Changes in Cognition and Alzheimer’s Disease Risk
Rachel Nosheny, PhDUniversity California San Francisco
Watch 16 min Slides PDF
2:00 - 2:30
Panel Discussion/ Q&A
Moderator: Alan Evans, PhD
Watch 20 min

2:30 - 5:25

Session 3

Synucleinopathies and MCI- Biology, Diagnosis, Progression and Treatment

Chair: James Galvin, MD, MPHUniversity of Miami Miller School of Medicine

2:30 - 2:35
Synucleinopathies and MCI: Background
2:35 - 3:10
Keynote The Role of Alpha-synuclein Aggregates in the Pathogenesis of Lewy Body and Parkinson’s Disease
Maria Grazia Spillantini, PhDUniversity of Cambridge
Watch 36 min Slides PDF
3:10 - 3:35
BREAK
3:35 - 3:55
Screening and Clinical Diagnosis of Lewy Body Disease
James Galvin, MD, MPHUniversity of Miami Miller School of Medicine
Watch 22 min Slides 1 PDF Slides 2 PDF
3:55 - 4:15
Biomarkers for LBD
David Irwin, MDUniversity of Pennsylvania
Watch 22 min Slides PDF
4:15 - 4:35
Treating Dementia with Lewy Bodies: Beyond Medications
Melissa Armstrong, MD, MSc, FAANUniversity of Florida
Watch 18 min Slides PDF
4:35 - 4:55
The Unraveling Story of Tyrosine Kinase Inhibition in Parkinson's Disease and Dementia with Lewy Bodies
Charbel Moussa, MBBS, PhDGeorgetown University
Watch 17 min Slides PDF
4:55 - 5:25
Panel Discussion/ Q&A
Moderator: Nikolaus McFarland, MD, PhD
Watch 31 min
5:25 - 5:35
Conclusions
Ranjan Duara, MD, FAANMount Sinai Medical Center
5:35 - 7:30
Networking Reception

Workshop

MCI and Dementia: From Epidemiology to Pathology

Sunday, January 19, 2020 · 8:30 am - 1:00 pm

7:30 am - 8:30
Continental Breakfast and Check-in

8:30 - 8:40

Chair: Zoe Arvanitakis, MD, MSRush University

8:30 - 8:40
MCI and Dementia: Reviewing the Spectrum from Epidemiology to Pathology
Ranjan Duara, MD, FAANMount Sinai Medical Center
8:40 - 9:15
Keynote The NIA-AA Research Framework: Implications for Clinical Care, Epidemiological and Genetic Studies
Sudha Seshadri, MDGlenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases
Watch 34 min Slides PDF
9:15 - 9:40
Risk Factors and Progression Rates of MCI
Mary Ganguli, MD, MPHUniversity of Pittsburgh
Watch 30 min Slides 1 PDF Slides 2 PDF
9:40 - 10:05
Cognitive Predictors of Disease Progression in Normal and At-risk States
Rosie Curiel Cid, PsyDUniversity of Miami
Slides PDF
10:05 - 10:30
BREAK
10:30 - 10:55
Sex and Neuropathology of Dementia
Zoe Arvanitakis, MD, MSRush University
Watch 27 min
10:55 - 11:20
Paradoxical Aging in Alzheimer’s Disease: A Clinicopathologic Perspective
Melissa Murray, PhDMayo Clinic
Watch 24 min Slides PDF
11:20 - 11:45
TDP43 Pathology - Effect of Demographic Factors
Gregory Jicha, MD, PhDUniversity of Kentucky
Watch 32 min Slides PDF
11:45 - 12:15 pm
Panel Discussion/Q&A
Moderator: Steven DeKosky, MD
Watch 29 min
12:15 - 12:30 pm
Conclusions
Ranjan Duara, MD, FAANMount Sinai Medical Center
12:30 - 1:00
LUNCH

Public Forum

Mild Cognitive Impairment: How We Detect It, What Causes it, How We Can Prevent It

Sunday, January 19, 2020 · 1:30 pm - 5:30 pm

1:00 - 1:30pm
Check-in and Refreshments

1:30 - 5:00

Chair: Sudha Seshadri, MDGlenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases

1:30 - 1:40
Mild Cognitive Impairment: Background and Importance
Ranjan Duara, MD, FAANMount Sinai Medical Center
1:40 - 2:15
Keynote How Your Lifestyle Can Protect Your Brain
Jennifer Rabin, PhDSunnybrook Research Institute
Watch 44 min
2:15 - 2:40
Who Gets MCI and What Happens to Them?
Mary Ganguli, MD, MPHUniversity of Pittsburgh
Watch 21 min
2:40 - 3:05
Web-based Technology to Screen and Monitor Cognitive Health
Rachel Nosheny, PhDUniversity California San Francisco
Watch 26 min
3:05 - 3:30
Everything You Wanted to Know About LBD but Were Afraid to Ask
James Galvin, MD, MPHUniversity of Miami Miller School of Medicine
Watch 26 min
3:30 - 3:55
BREAK
3:55 - 4:20
Inside the Brain in MCI
Zoe Arvanitakis, MD, MSRush University
Watch 26 min
4:20 - 4:45
Memory Compensation Training and Computerized Cognitive Training in MCI
Glenn Smith, PhD, ABPPUniversity of Florida
Watch 33 min Slides PDF
4:45 - 5:15
Panel Discussion and Q&A
Watch 33 min
5:15 - 5:30
Conclusions
Ranjan Duara, MD, FAANMount Sinai Medical Center

Programs, recordings and slides as published at the time. Slides and recordings appear only where speakers chose to share them. Affiliations are as of 2020.