14th Annual · January 2016 · In person
2016
- 28 faculty
- 33 recordings
- 26 slide decks
Symposium
Risk Factors for Cognitive Decline: Cardiovascular Disease, Inflammation and Subjective Symptoms
Saturday, January 16, 2016 · 8:00 am - 7:30 pm
- 7:00 - 8:00amContinental Breakfast and Check-in
- 8:00 - 8:15
- 8:15 - 9:00Keynote Genes, AD Pathology, Cerebrovascular Disease, and AD Dementia
9:00 - 12:30
Mini-Symposium 1
Vascular Disease, Neuroinflammation and Cognition
Chair: Charles DeCarli, MDUniversity of California, Davis
- 9:00 - 9:20Aging, Alzheimer Disease and Vascular Pathology: Which are the Determinants of Cognitive Impairment?
- 9:20 - 9:40Innate Immune Activation in Neurodegenerative Disease: Differential Effects on Amyloid and Tau Pathology
- 9:40 - 10:00Genetic Pathways Linking Neuroinflammation, Vascular Disease and Neurodegeneration
- 10:00 - 10:30BREAK
- 10:30 - 10:50Impact of Vascular Risk Factors on Cognition Independent of Amyloid and MRI Measures of AD and CVD
- 10:50 - 11:10Systemic Inflammation Triggers Acute Delirium, Brain Injury and Contributes to Accelerated Neurodegeneration
- 11:10 - 11:30Markers of Inflammation and Immune Activation, Small Vessel Disease, Amyloid Deposition and Progression to Dementia in Non-Demented Individuals
- 11:30 - 11:50Lifestyle Intervention To Prevent Cognitive Impairment
- 11:50am - 12:50pm
- 12:50 - 1:50LUNCH
1:50 - 5:20
Mini-Symposium 2
Subjective Cognitive Impairment: Epidemiology, Biomarkers, and Progression
Chair: Mary Ganguli, MD, MPHUniversity of Pittsburgh
- 1:50 - 2:10The Epidemiological Relevance of Subjective Cognitive Decline
- 2:10 - 2:30Subjective Cognitive Concerns and Biomarker Evidence of Preclinical Alzheimer’s Disease
- 2:30 - 2:50Subjective Cognitive Impairment, Neuroticism and Brain Amyloid Load
- 2:50 - 3:10Family History, Subjective Memory Complaints and Brain Amyloid Load in the ADNI Study
- 3:10 - 3:40BREAK
- 3:40 - 4:00Neuropathology Among Cognitively Normal Brain Donors, With & Without Subjective Memory Complaints
- 4:00 - 4:20APOE e4, Subjective Memory Symptoms and Cognitive Decline
- 4:20 - 5:20
- 5:20 - 7:30NETWORKING RECEPTION
Workshop
Diagnosis of Preclinical and Prodromal Alzheimeru2019s Disease
Sunday, January 17, 2016 · 8:30 am - 1:30 pm
- 7:00 - 8:00 amContinental Breakfast and Check-in
- 8:00 - 8:15Introduction to the Workshop
- 8:15 - 9:00Keynote KEYNOTE LECTURE: The Prevalence of Amyloid Positivity by Age, APOE Genotype and Cognitive Status - Implications for the Diagnosis of Alzheimer’s Disease
9:00 - 12:30
Diagnosis of Preclinical and Prodromal Alzheimer's Disease
Chair: David Knopman, MDMayo Clinic Rochester
- 9:00 - 9:20Biomarker Patterns in Subtypes of Alzheimer’s Disease - Implications for Pathophysiology and Diagnosis
- 9:20 - 9:40Detection of Preclinical Alzheimer’s Disease: Implications for Prevention Trials
- 9:40 - 10:00The Added Value of the International Working Group - 2 Diagnostic Criteria for Alzheimer’s Disease
- 10:00 - 10:30BREAK
- 10:30 - 10:50Diagnostic Complexities in Current Clinical and Morphological Criteria for Alzheimer's Disease
- 10:50 - 11:10A Canadian Consensus: Defining MCI for Clinical and Research Purposes
- 11:10 - 11:30Harmonized Clinical Diagnostic Criteria for the Incipient Symptomatic Stages of Alzheimer’s Disease
- 11:30am - 12:30pm
- 12:30pm - 1:30pmLUNCH
Public Forum
Memory Complaints and the Early Diagnosis of Alzheimer's Disease
Sunday, January 17, 2016 · 1:30 pm - 5:40 pm
- 1:00 - 1:30pmCheck-in and Refreshments
- 1:30 - 1:35
1:35 - 5:30
Chair: Steven DeKosky, MDUniversity of Florida
- 1:35 - 1:45Introduction to the Educational Forum
- 1:45 - 2:10Alzheimer Disease: Between the Inevitable and the Modifiable
- 2:10 - 2:35What are Subjective Memory Complaints and What is their Significance?
- 2:35 - 3:00Why is an Early Diagnosis of Alzheimer’s Important and How Do We Achieve It?
- 3:00 - 3:30BREAK
- 3:30 - 3:55The Link Between Depression, Anxiety and Alzheimer’s Disease
- 3:55 - 4:20What have we Learned from Brain Autopsies of Persons with and without Dementia
- 4:20 - 4:45The Importance of Participating in Clinical Trials in Alzheimer’s Disease
- 4:45 - 5:30
Programs, recordings and slides as published at the time. Slides and recordings appear only where speakers chose to share them. Affiliations are as of 2016.