Program
20th ANNUAL MILD COGNITIVE IMPAIRMENT SYMPOSIUM
Saturday, February 26, 2022 (10:00 am – 3:15 pm US Eastern Time)
Sunday, February 27, 2022 (10:00 am – 3:00 pm US Eastern Time)
THE ANNUAL ALZHEIMER’S PUBLIC EDUCATIONAL FORUM
Sunday, March 6, 2022 (1:30 pm – 3:30 pm US Eastern Time)
Schedule
MCI Symposium Program (Day 1)
Saturday, February 26, 2022
All times in US Eastern Time.
10:00
Introductory Notes on the 20th Annual MCI Symposium
10:15
Reflection on the Concept of MCI and the Evolution of the Term “Adult Cognitive Disorders”
10:35
SESSION 1: COVID-19, MCI and Dementia
10:40
Keynote: The Global Effort to Study the Short-and Long-term consequences of SARS-CoV-2 on the CNS
11:10
Clinical Features and Plasma Biomarkers of Neurodegeneration and Neuroinflammation in Hospitalized COVID-19 Patients
11:30
Pathogenesis and Neurological Manifestations of COVID-19 Infection
11:50
Neurologic Post-acute Sequelae of SARS-CoV-2 Infection
12:10
Impact of COVID on Persons with AD: Focus on Hispanics/Native Americans
12:30
Panel Discussion/Q&A
12:50
Break
13:00
SESSION 2: Heterogeneity of Alzheimer’s Disease
13:05
Keynote: Symptomatic, Cognitive and Biomarker Heterogeneity in the Preclinical and Prodromal Stages of Alzheimer’s Disease
13:35
LATE: What It Is and Relevance to MCI
13:55
Genomic Heterogeneity in AD
14:15
A Multiomics Approach to Heterogeneity in Alzheimer’s
14:35
Embracing Heterogeneity in Early-phase Clinical Trial Designs for AD/ADRD
14:55
Panel Discussion/Q&A
15:15
End of Day 1
10:00
Ranjan Duara, MD, MRCP, FAAN
Mount Sinai Medical Center
Mount Sinai Medical Center
10:15
Ron Petersen, MD, PhD
Mayo Clinic
Mayo Clinic
10:35
Chair: Sudha Seshadri, MD
UTHSCSA
UTHSCSA
10:40
Sudha Seshadri, MD
UTHSCSA
UTHSCSA
11:10
Thomas Wisniewski, MD
New York University
New York University
11:30
Serena Spudich, MD, MA
Yale University
Yale University
11:50
Igor Koralnik, MD
Northwestern University
Northwestern University
12:10
Gabriel Erausquin, MD, PhD, MSc
UTHSCSA
UTHSCSA
12:30
Panel Discussion/Q&A
12:50
Break
13:00
Chair: Steve DeKosky, MD
University of Florida
University of Florida
13:05
David Wolk, PhD
University of Pennsylvania Perelman School of Medicine
University of Pennsylvania Perelman School of Medicine
13:35
Peter Nelson, MD, PhD
University of Kentucky College of Med.
University of Kentucky College of Med.
13:55
Nilüfer Ertekin-Taner, MD, PhD
Mayo Clinic
Mayo Clinic
14:15
Amanpreet Badhwar, PhD
University of Montreal
University of Montreal
14:35
Steven Arnold, MD
MGH, Harvard
MGH, Harvard
14:55
Panel Discussion/Q&A
15:15
End of Day 1
MCI Symposium Program (Day 2)
Sunday, February 27, 2022
All times in US Eastern Time.
10:00
SESSION 3: Predicting Progression & Cognitive Decline in AD and Impact on Clinical Trial Design
10:05
Keynote: Regional Accumulation of Tau in the Brain is a Major Determinant of Rate of Progression
10:35
Novel Approaches to Efficiently Identify Progression to SCD and MCI for AD Clinical Research
10:55
The Role of Brain Connectivity in the Spreading of Tau Pathology in AD
11:15
Preserving Cognitive Reserve with Social Interaction
11:35
Incorporating Factors Associated with Rate of Progression into the Design of AD Clinical Trials
11:55
Improved Designs for AD Clinical Treatment Trials
12:15
Panel Discussion/Q&A
12:35
Break
12:45
SESSION 4: Neuropsychiatric Features of MCI
12:50
Keynote: Will Targeting Neuropsychiatric Symptoms in Prodromal AD Delay or Prevent Progression to Dementia?
13:20
Challenges in the Measurement of Neuropsychiatric Symptoms (NPS) in MCI and Dementia (Caregiver Report and Objective Assessment)
13:40
Association of Biomarkers (sMRI, fMRI, FDG-PET, Amyloid PET, Tau PET) with Neuropsychiatric Symptoms in MBI, MCI and Dementia
14:00
Mild Behavioral Impairment, Prevalence, Caregiver Burden and Management
14:20
Neuropsychiatric Features of Lewy Body Disease
14:40
Panel Discussion/Q&A
15:00
Concluding Remarks
15:15
END OF SYMPOSIUM
10:00
Chair: Philip Scheltens, MD, PhD
Amsterdam University Medical Centers
Amsterdam University Medical Centers
10:05
Bradley Hyman, MD, PhD
MGH/Harvard University
MGH/Harvard University
10:35
Rachel Nosheny, PhD
UCSF
UCSF
10:55
Nicolai Franzmeier, MD, PhD
University of Muenchen
University of Muenchen
11:15
Hiroko Dodge, PhD
OHSU
OHSU
11:35
Philip Scheltens, MD, PhD
Amsterdam University Medical Centers
Amsterdam University Medical Centers
11:55
Howard Feldman, MD, FRCP (C)
University of California, San Diego
University of California, San Diego
12:15
Panel Discussion/Q&A
12:35
Break
12:45
Chair: Mary Ganguli, MD, MPH
University of Pittsburgh
University of Pittsburgh
12:50
Constantine (Kostas) Lyketsos, MD, MHS
Johns Hopkins University
Johns Hopkins University
13:20
Matthew Peters, MD
Johns Hopkins University
Johns Hopkins University
13:40
Pedro Rosa-Neto, MD, PhD
McGill University
McGill University
14:00
Zahinoor Ismail, MD
University of Calgary
University of Calgary
14:20
Paul Donaghy, MD
Newcastle University
Newcastle University
14:40
Panel Discussion/Q&A
15:00
Ranjan Duara, MD, MRCP, FAAN
Mount Sinai Medical Center
Mount Sinai Medical Center
15:15
END OF SYMPOSIUM
Public Educational Forum Program
Sunday, March 6, 2022
1:30 PM US Eastern Time.
The Countdown Begins!
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